Environmental perchlorate exposure

Perchlorate as an environmental contaminant.

Perchlorate anion (ClO4-) has been found in drinking water supplies throughout the southwestern United States. It is primarily associated with releases of ammonium perchlorate by defense contractors, military operations, and aerospace programs. Ammonium perchlorate is used as a solid oxidant in missile and rocket propulsion systems. Traces of perchlorate are found in Chile saltpeter, but the us...

Developmental Perchlorate Exposure: Gilbert Responds

The epidemiology of environmental perchlorate exposure and thyroid function: a comprehensive review.

OBJECTIVE To review the epidemiological literature relevant to evaluating the risk of adverse effects on thyroid function associated with environmental perchlorate exposure. METHODS All studies investigating possible adverse effects of environmental perchlorate exposure on thyroid function in adults or in pregnant women and their newborns were critically evaluated. RESULTS There is no credi...

Environmental factors that control microbial perchlorate reduction.

As part of a study to elucidate the environmental parameters that control microbial perchlorate respiration, we investigated the reduction of perchlorate by the dissimilatory perchlorate reducer Dechlorosoma suillum under a diverse set of environmental conditions. Our results demonstrated that perchlorate reduction by D. suillum only occurred under anaerobic conditions in the presence of perchl...

Health Effects Assessment for Environmental Perchlorate Contamination

1386. Toxicol Sci 60:291–292 (2001). 26. Narayanan L, Yu KY, Mattie DR, Fisher JW. Perchlorate induced thyroid hormonal changes in pregnant and lactating female rats, fetuses and nursing pups. Abstract 2069. Toxicol Sci 60:434 (2001). 27. Fisher J, Todd P, Mattie D, Godfrey D, Narayanan L, Yu K. Preliminary development of a physiological model for perchlorate in the adult male rat: a framework ...